Prof. Park Jae-Young’s Team Develops a Cancer Diagnosis Sensor Using 3D Porous Graphene
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- 2021-11-10
- 2027
Prof. Park Jae-Young’s Team Develops a Cancer Diagnosis Sensor Using 3D Porous Graphene
Professor
Park Jae-Young's research team (Department of Electronic Engineering) has
succeeded in developing a three-dimensional porous graphene flexible electrode
material with excellent mechanical, electrical and chemical performance, which
is a key technology for the development of various wearable medical/healthcare
sensors and energy storage devices. The developed technology is evaluated as a
technology with high commercialization potential because it can produce
materials and devices using only laser processing and coating technology, which
enables low cost and mass production.
Professor Park Jae-Young (left) and Ph.D. student Abu doctoral (right)?
Recently, due to the unique structure,
excellent thermal conductivity, high surface area, and excellent electrical
conductivity of 3D porous graphene (3DPG) electrode material fabricated with a
laser, research for application and utilization in the field of biosensors and
energy storage devices has been conducted. A lot is being done however,
three-dimensional porous graphene flakes made with laser processing technology
have unstable interconnections, so their electrical conductivity is not
constant, and their mechanical strength is weak, so there is a limit as a
commercial technology.
In addition, when the sensor and energy storage element
using the same were repeatedly bent, structural deformation was greatly
induced, and electrical conductivity was greatly reduced. In order to solve
this problem, studies have been conducted to coat 3D porous graphene with phosphorane
(Ph), a 2D nanomaterial with excellent mechanical flexibility and
biocompatibility, but this material deteriorates in performance and
structurally when exposed to the external environment. Because it is easily
damaged and there is no active functional group, there has been a limit to realizing
a sensor and energy storage device with excellent performance.
Accordingly, Professor Park Jae-Young's team
successfully solved the problems of non-uniform electrical conductivity and
easily broken or deformed structures by coating phosphorine encapsulated with
polyaziridine (PAZ) on three-dimensional porous graphene. The non-covalent
encapsulation technique using polyaziridine (PAZ) was very effective in
alleviating the instability of phosphorine upon environmental exposure,
self-aggregation and re-stacking, lack of active functional groups, and coffee
ring effect. In addition, the electrochemical properties and surface-active
functionality of the electrode material were greatly improved through the
bridging effect linking 2D phosphorene and 3D porous graphene.
In addition, the research team has successfully
developed a high-performance wearable cancer diagnostic sensor,
electrocardiogram (ECG) sensor, and micro supercapacitor using a
three-dimensional porous graphene flexible electrode material coated with
phosphorin encapsulated with polyaziridine. The cancer diagnostic sensor showed
a linear range of 0.1-700 pgmL-1 and 1-100 ngmL-1, a detection limit of 0.34
pgmL-1, and high selectivity. The finger touch-based ECG sensor showed
relatively low and stable impedance at the skin electrode interface, and the
measured signal-to-noise ratio (13.5 dB) of the sensor was similar to that of
the Ag/AgCl commercial electrode (13.9 dB) sensor. In addition, the micro
supercapacitor exhibited excellent capacitance characteristics of 16.94mF cm-2.
These results proved that the excellent properties of the three-dimensional
porous flexible electrode material developed in this study and the
manufacturing process technology capable of mass production can be widely used
in various industrial fields.
Meanwhile,
this research was carried out with support from the National Research
Foundation of Korea Biomedical Technology Development Project
(NRF-2017M3A9F1031270) and the Ministry of Trade, Industry and Energy's Nano
Convergence Industry Core Technology Development Project (20000773). The
research results were published as a cover paper in the June 2021 issue of
Advanced Functional Materials (IF:18.808) published by Wiley, Germany, the
world's leading journal dedicated to research on functional materials and
devices.
https://doi.org/10.1002/adfm.202009018
Concept diagram of high-performance 3D porous graphene electrode and performance of the manufactured cancer diagnostic sensor, electrocardiogram sensor, and micro supercapacitor
Cover published in Advanced Functional Materials